Name: Irresistibly Cheesy Bubble Up Biscuit Pizza Casserole Bliss
Prep time: 10 min
Cook time: 30 min
Total time: 40 min
Ingredients: 16 oz Refrigerated Biscuit Dough (Consider homemade for a richer flavor.); 1 cup Pizza Sauce (Swap with homemade for a personal touch.); 1.5 cups Shredded Mozzarella Cheese (Try a blend or cheddar for a twist.); 1 cup Pepperoni Slices (Use sausage or veggies for a different take.); 1 tsp Italian Seasoning (Feel free to increase for extra zest.); 2 tbsp Chopped Fresh Parsley (A lovely garnish that can be omitted.)

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Picture this: the enticing aroma of gooey cheese melting in the oven, mingling with the rich scent of pizza sauce and savory herbs. That’s the magic of the Cheesy Bubble Up Biscuit Pizza Casserole, a dish born from the joyful chaos of a busy kitchen. One evening, while trying to spice up our usual dinner routine, I discovered this delightful mashup that effortlessly satisfies cravings for both pizza and comforting casseroles.

In just 40 minutes, you can whip up a family-friendly meal that brings everyone to the table, eager for seconds. Fluffy biscuit pieces soak up the savory flavors of the sauce, while crispy pepperoni and melty mozzarella create a dish that’s as easy to customize as it is to devour. Trust me when I say, it’s a weeknight winner that turns a simple dinner into a memorable feast you’ll want to make again and again. Ready to dive in? Let’s get cooking!

Why will you love this Cheesy Bubble Up Biscuit Pizza Casserole?

Quick preparation: In just 40 minutes, you can create a delightful dish that pleases even the pickiest eaters.

Family-friendly: This meal is perfect for gathering around the table—everyone can customize their toppings!

Comfort food delight: Combining cheesy goodness and savory pizza flavors makes for a cozy meal that everyone craves.

Versatile options: Change up toppings based on what’s in your fridge or personal preferences, from veggies to different cheeses.

Satisfying texture: The fluffy biscuits create a unique balance with gooey cheese and crispy edges, making every bite a treat.

Make sure to check out our tips on storage or make-ahead options to simplify your weeknight dinners!

Cheesy Bubble Up Biscuit Pizza Casserole Ingredients

For the Casserole
Refrigerated Biscuit Dough (16 oz) – Serves as a fluffy base; consider homemade for a richer flavor.
Pizza Sauce (1 cup) – Adds delicious moisture and tomato richness; swap with homemade for a personal touch.
Shredded Mozzarella Cheese (1.5 cups) – Provides creamy melt; try a blend or cheddar for a twist.
Pepperoni Slices (1 cup) – A classic topping that enhances flavor; use sausage or veggies for a different take.
Italian Seasoning (1 tsp) – Essential for authentic pizza taste; feel free to increase for extra zest.
Chopped Fresh Parsley (2 tbsp, optional) – A lovely garnish that brings freshness to the dish; omit if not preferred.

These ingredients combine to create the irresistible Cheesy Bubble Up Biscuit Pizza Casserole that your family will love!

How to Make Cheesy Bubble Up Biscuit Pizza Casserole

Preheat your oven to 350°F (175°C) and grease a 9×13-inch baking dish to prevent sticking and ensure your casserole bakes evenly.
Cut each refrigerated biscuit into four equal pieces. This allows for even cooking and ensures each bite is perfectly fluffy.
Mix the biscuit pieces in a bowl with the pizza sauce and half of the mozzarella cheese. Stir until the biscuit pieces are well-coated in that luscious, savory sauce.
Pour the biscuit mixture into your greased baking dish, spreading it out evenly to create the perfect base for this cheesy goodness.
Top the casserole with the remaining mozzarella and arrange the pepperoni slices on top. Don’t forget to sprinkle with Italian seasoning for an added flavor boost.
Bake uncovered for 25-30 minutes, or until the biscuits are puffed, golden, and the cheese is bubbling over the top. If they brown too quickly, cover with foil.
Let the casserole sit for 5 minutes before serving. Garnish with fresh parsley if desired to add a pop of color and freshness!

Optional: Serve with a side salad for a wholesome meal.

Exact quantities are listed in the recipe card below.

Storage Tips for Cheesy Bubble Up Biscuit Pizza Casserole

Room Temperature: The casserole should not be left at room temperature for more than 2 hours to maintain food safety.
Fridge: Store leftovers in an airtight container in the refrigerator for up to 4 days. Reheat in the microwave or oven until warmed through.
Freezer: Wrap tightly with plastic wrap and foil, or use a freezer-safe container to freeze for up to 2 months. Thaw overnight in the fridge before reheating.
Reheating: When reheating, warm in the oven at 350°F (175°C) until heated thoroughly, about 20-25 minutes, for the best texture.

Make Ahead Options

These Cheesy Bubble Up Biscuit Pizza Casserole are perfect for busy weeknights and make-ahead meal prep! You can assemble the casserole up to 24 hours in advance by mixing the cut biscuit pieces with pizza sauce and half of the mozzarella, then placing the mixture in a greased baking dish. Cover it tightly with plastic wrap and refrigerate. Just before baking, let it sit at room temperature for about 15 minutes, then top with the remaining mozzarella and pepperoni. Bake as instructed for delicious results that are just as satisfying, saving you valuable time when hunger strikes!

Expert Tips for Cheesy Bubble Up Biscuit Pizza Casserole

Even Biscuit Cutting: Make sure the biscuit pieces are cut evenly to ensure they cook uniformly and absorb the pizza sauce perfectly.
Crispier Edges: For extra crispy edges, place your baking dish on the bottom rack of the oven, giving a delightful crunch to the casserole.
Make Ahead: Assemble your casserole a few hours in advance and refrigerate. Let it sit at room temperature for about 15 minutes before baking to avoid uneven cooking.
Check for Doneness: Keep an eye on the casserole during the last few minutes of baking. If it browns too quickly, cover it with foil to allow the biscuits to cook through without burning.
Customize Toppings: Don’t hesitate to swap toppings in your Cheesy Bubble Up Biscuit Pizza Casserole! Vegetables, different cheeses, or meats can tailor the dish to your cravings and dietary needs.

What to Serve with Cheesy Bubble Up Biscuit Pizza Casserole?

Elevate your meal by pairing this delectable dish with a few delightful sides that balance flavors and textures.

Fresh Garden Salad: A crisp, refreshing salad with mixed greens and a light vinaigrette offers a perfect counterbalance to the richness of the casserole.
Garlic Breadsticks: Soft, warm breadsticks infused with garlic butter add a comforting touch, perfect for mopping up any leftover pizza sauce.
Steamed Broccoli: Tender broccoli brings a vibrant green element to the table, providing a nutrient-dense side that complements the hearty casserole.
Cheesy Garlic Mashed Potatoes: For an indulgent twist, creamy mashed potatoes infused with garlic and cheese create a heavenly comfort food fusion. The extra creaminess mirrors the gooeyness of the casserole, making it a cozy duo!
Zesty Coleslaw: A tangy coleslaw adds a crunchy texture and a burst of acidity, which brightens every bite and cuts through the richness of the casserole beautifully.
Red Wine: A glass of medium-bodied red wine, like a Chianti or Merlot, can enhance the savory flavors of the casserole, making your dinner feel even more special.

Dive into these suggestions to create a memorable dining experience that everyone will cherish!

Cheesy Bubble Up Biscuit Pizza Casserole Variations

Customize your casserole with these fun and flavorful variations that will delight your taste buds!

Veggie Delight: Replace the pepperoni with spinach, bell peppers, and mushrooms for a fresh, garden-inspired twist. This adds vibrant colors and healthful nutrients, perfect for a meatless night.
Spicy Kick: Add jalapeños or crushed red pepper flakes to the pizza sauce for an extra punch. If you love heat, this will transform your dish into a zesty treat that bites back!
Cheddar Twist: Use sharp cheddar cheese in place of mozzarella for a bolder flavor. The rich, tangy cheddar melts beautifully, offering a new dimension to your favorite casserole.
BBQ Chicken: Swap pizza sauce for barbecue sauce and replace pepperoni with shredded cooked chicken for a sweet and smoky flavor profile. The combination will take your taste buds on a delicious detour!
Herb Infusion: Mix fresh or dried herbs like basil and oregano into the biscuit mixture for a fragrant kick. This little addition will elevate the overall aroma and taste, making each forkful even more irresistible.
Breakfast Style: Transform this into a breakfast dish by adding scrambled eggs, bacon, and cheese. It’s a delightful way to start the day or enjoy breakfast-for-dinner!
Creamy Spin: Stir in a bit of cream cheese or ricotta with the mozzarella for a creamier texture. This twist will create a luscious base that makes each bite comforting and rich.
Gluten-Free Option: Use gluten-free biscuit dough and pizza sauce to make this dish suitable for those with dietary restrictions. Everyone deserves to enjoy this cozy casserole!

Cheesy Bubble Up Biscuit Pizza Casserole Recipe FAQs

What type of biscuit dough should I use for the casserole?
I recommend using refrigerated biscuit dough for convenience, but feel free to swap it out with homemade biscuit dough for an enhanced flavor profile. The goal is to have a fluffy base that will soak up the flavors of the pizza sauce beautifully.

How should I store leftovers of the Cheesy Bubble Up Biscuit Pizza Casserole?
Leftovers can be stored in an airtight container in the refrigerator for up to 4 days. It’s a great idea to reheat individual portions in the microwave for a quick meal or warm the whole dish in the oven until heated through.

Can I freeze the Cheesy Bubble Up Biscuit Pizza Casserole?
Absolutely! You can wrap the casserole tightly with plastic wrap or foil and freeze it for up to 2 months. To freeze, let it cool completely after baking, then wrap it to ensure it doesn’t absorb any freezer odors. When ready to enjoy, thaw it overnight in the fridge and reheat in the oven at 350°F (175°C) for about 20-25 minutes until warmed through.

What can I do if my casserole is browning too quickly in the oven?
If you notice the casserole browning faster than expected, simply cover it loosely with foil during the last few minutes of baking. This will allow the biscuits to cook through without the top getting overly browned.

Are there any dietary considerations for this recipe?
Yes! This casserole can easily be made vegetarian by omitting the pepperoni or replacing it with your favorite vegetables. For gluten-free needs, consider using gluten-free biscuit dough. Always check the labels of your ingredients if allergies are a concern, especially for dairy and gluten.

How long do I need to let the casserole sit before serving?
Let the casserole sit for about 5 minutes before serving. This resting period helps it set slightly, making it easier to serve while keeping those delicious cheesy edges intact!

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